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Inpatient Postoperative Mortality: Comparing Patients Hospitalized Preoperatively to Those Having Elective Surgery.

Anesthesiology2025-03-27PubMed
Total: 77.5Innovation: 8Impact: 9Rigor: 7Citation: 8

Summary

In a statewide cohort of 1.25 million adult major surgeries, approximately 95% of in-hospital postoperative deaths occurred after nonelective surgery, which also comprised 70% of cases. Elective surgery had a markedly lower relative risk of death (0.13) and fewer major complications. The study urges shifting public health and quality improvement strategies toward patients already hospitalized preoperatively and trauma-related surgeries.

Key Findings

  • Nonelective surgeries accounted for 94.5% of 20,874 in-hospital postoperative deaths and 70% of hospitalizations.
  • Elective surgery had a relative risk of death of 0.13 (95% CI 0.12–0.14) versus nonelective.
  • Major complications (AKI, hospital-acquired pneumonia, MACE, infection) were all less frequent in elective cases.

Clinical Implications

Benchmark elective surgery mortality separately from nonelective. Prioritize perioperative optimization, monitoring, and postoperative care pathways for already-admitted and trauma surgery patients, where the mortality burden resides.

Why It Matters

This reframes perioperative mortality benchmarking by distinguishing elective from nonelective surgery, directly informing resource allocation and QI targets in anesthesiology and perioperative medicine.

Limitations

  • Retrospective design with potential coding and residual confounding
  • Single-state data (Florida, 2021–2022) and in-hospital outcomes only

Future Directions

Develop risk-adjusted, nonelective-specific perioperative mortality metrics and test targeted interventions for inpatient surgical populations including trauma.

Study Information

Study Type
Cohort
Research Domain
Prognosis
Evidence Level
III - Large retrospective cohort assessing outcomes across elective vs nonelective surgeries
Study Design
OTHER