Daily Ards Research Analysis

BACKGROUND: Increased time to surgery is a well-established risk factor for complication and mortality among patients undergoing hip fracture fixation. However, few studies have been completed evaluating the association between time to surgery and complication rates in patients undergoing operative fixation of pelvic ring injuries. METHODS: A retrospective cohort study was performed at a Level I trauma center including all patients with operative pelvic ring injuries from 2015 to 2022. Time from hospital admission to surgery, basic demographics, and comorbidities were determined for all patients. Systemic complications including acute respiratory distress syndrome, pneumonia, sepsis, deep venous thrombosis, pulmonary embolus, ileus, acute kidney injury, myocardial infarction, and mortality were recorded. The association between time to surgery and overall complications and each complication individually was estimated using multivariable statistical models. RESULTS: A total of 1,056 patients were included in the final cohort. Patients who underwent surgery within 48 hours (n = 724) had an overall lower complication rate (17.8%) compared with those patients (n = 332) who underwent surgery greater than 48 hours after admission (34.9%). Each additional hour delay to surgery from admission was associated with a 0.4% increased odds of any complication. With respect to specific complications, each additional hour also increased the odds of sepsis (0.7%), deep venous thrombosis (0.3%), acute kidney injury (0.3%), myocardial infarction (0.5%), and pneumonia (0.4%). The odds of overall complication was 2.10 when patients underwent surgery within 42 hours after admission and increased at every time point afterwards. CONCLUSION: Among patients with pelvic ring injuries, increased time to surgery was associated with an increased odds of systemic complication. This underscores the importance of aggressive resuscitation and prompt surgical intervention to reduce morbidity and improve overall patient outcomes. LEVEL OF EVIDENCE: Prognostic and Epidemiological; Level III.

OBJECTIVE: To find out the risk factors for respiratory distress syndrome in late preterm infants. METHODS: This was a retrospective study. A total of 1605 premature infants born in Maternity & Child Care Center of Qinhuangdao from January 2020 to June 2023 were selected as the research subjects. They were divided into RDS group and non RDS group based on the presence or absence of respiratory distress syndrome(RDS). The clinical pathological characteristics of the two groups of patients were compared. Logistic regression analysis was used to analyze the risk factors for respiratory distress syndrome in late stage premature infants. RESULTS: The results of univariate analysis showed that there was no statistically significant difference in neonatal weight, placental abnormalities, gestational hypertension, and maternal age between the RDS group and the non RDS group(P>0.05). There were significant differences in gender, whether premature rupture of membranes, whether cesarean section, and diabetes during pregnancy(P<0.05). The binary logistic regression analysis showed that gender(male), cesarean section(yes) and diabetes in pregnancy(yes) were all risk factors for RDS in preterm infants (P<0.05). Premature rupture of membranes is a protective factor for RDS in premature infants (P<0.05). Gender (male), cesarean section(yes), and diabetes in pregnancy(yes) were all risk factors for poor prognosis of RDS children(P<0.05). Premature rupture of membranes (PROM) is a protective factor for poor prognosis in premature infants (P<0.05). CONCLUSION: Male sex, cesarean section, and diabetes in pregnancy may be the risk factors for RDS and poor prognosis of premature infants.

BACKGROUND: Despite of millions of people who suffered from coronavirus disease 2019 (COVID-19) infection, pulmonary functions of these patients are sparsely reflected in the literature. Although few researchers have performed pulmonary function tests to evaluate the respiratory function of COVID-19 patients after recovery from acute illness, the sample size was too limited. The present study was conducted in a tertiary care hospital with an aim to determine pulmonary functions of COVID-19 patients recovered from acute illness. METHODS: A total of 250 COVID-19 patients who recovered from acute illness were included in the study. Pulmonary function test of these patients was performed; the indices of PFT studied included, forced expiratory volume in the first second (FEV RESULTS: Even after >3 months of recovery from the COVID-19 acute illness, patients had respiratory complaints like cough and shortness of breath. These convalescent patients also reported to have certain psychological issues like feeling of loneliness, fear, anxiety, and depression. It was noted that all the respiratory parameters of patients even after >3 months of recovery from the COVID-19 acute illness were compromised. CONCLUSION: The pulmonary functions of the patients recovered from COVID-19 infection should be evaluated before discharge of the patient from hospital followed by periodic evaluation post discharge, so that necessary therapeutic interventions can be initiated. Breathing exercises and pranayama can augment the better outcome of these patients. Pulmonary function tests are not only recommended but also are necessary for monitoring of patients who have recovered from COVID-19 infection.