Longer time to surgery for pelvic ring injuries is associated with increased systemic complications.
Summary
In a Level I trauma center cohort of 1,056 pelvic ring injury surgeries, operations within 48 hours had significantly fewer complications than those after 48 hours (17.8% vs 34.9%). Each additional hour of delay increased the odds of any complication by 0.4% and raised risks of sepsis, pneumonia, AKI, MI, and DVT; findings support expedited surgery and robust early resuscitation.
Key Findings
- 48-hour surgery threshold associated with lower overall complications (17.8% vs 34.9%).
- Each additional hour delay increased odds of any complication by 0.4%.
- Hourly delays raised odds of specific complications: sepsis (+0.7%), pneumonia (+0.4%), DVT (+0.3%), AKI (+0.3%), MI (+0.5%).
- Model suggested an inflection around 42 hours with rising overall complication odds thereafter.
Clinical Implications
Prioritize surgery within 48 hours for operable pelvic ring injuries when feasible; implement early resuscitation and surveillance for sepsis, pneumonia, ARDS, and thromboembolic events when delays are unavoidable.
Why It Matters
Identifies a modifiable system-level factor—time to surgery—affecting systemic complications including ARDS, informing protocols for trauma care optimization.
Limitations
- Retrospective single-center design limits causal inference and generalizability
- Potential residual confounding (injury severity, resuscitation quality) not fully captured
Future Directions
Prospective multicenter studies to validate time thresholds and evaluate protocols prioritizing expedited fixation; assess causal effects via quasi-experimental designs.
Study Information
- Study Type
- Cohort
- Research Domain
- Prognosis
- Evidence Level
- III - Retrospective cohort study with multivariable adjustment
- Study Design
- OTHER