Cardiology - Paper Rankings

Papers ranked by AI-analyzed total score

Rank	Paper Title	Total	Innovation	Impact	Rigor	Citation
1	Engineered heart muscle allografts for heart repair in primates and humans. Nature • 2025-01-30	94.5	10	9	9	10
2	Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography. Nature medicine • 2025-02-11	91.5	9	9	9	10
3	Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk. Nature genetics • 2025-03-07	91.5	9	9	9	10
4	Maternal high-fat diet exacerbates atherosclerosis development in offspring through epigenetic memory. Nature cardiovascular research • 2025-03-16	90.0	9	9	9	9
5	Abelacimab versus Rivaroxaban in Patients with Atrial Fibrillation. The New England journal of medicine • 2025-01-22	90.0	9	9	9	9
6	Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis. Nature cardiovascular research • 2025-01-11	90.0	9	9	9	9
7	Genomic analysis of 11,555 probands identifies 60 dominant congenital heart disease genes. Proceedings of the National Academy of Sciences of the United States of America • 2025-03-24	90.0	9	9	9	9
8	S-Nitrosylation of Pyruvate Kinase Isoform 2 Drives Cardiac Fibrosis by Promoting Mitochondrial Fission. Circulation • 2025-12-10	90.0	9	9	9	9
9	Dynamic molecular atlas of cardiac fibrosis at single-cell resolution shows CD248 in cardiac fibroblasts orchestrates interactions with immune cells. Nature cardiovascular research • 2025-03-28	90.0	9	9	9	9
10	Meta-prediction of coronary artery disease risk. Nature medicine • 2025-04-17	90.0	9	9	9	9
11	Effect of sotagliflozin on major adverse cardiovascular events: a prespecified secondary analysis of the SCORED randomised trial. The lancet. Diabetes & endocrinology • 2025-02-18	90.0	9	9	9	9
12	The gut microbiota-bile acid-TGR5 axis orchestrates platelet activation and atherothrombosis. Nature cardiovascular research • 2025-04-12	90.0	9	9	9	9
13	Modified mRNA Treatment Restores Cardiac Function in Desmocollin-2-Deficient Mouse Models of Arrhythmogenic Right Ventricular Cardiomyopathy. Circulation • 2025-04-11	90.0	9	9	9	9
14	Endothelial cell-related genetic variants identify LDL cholesterol-sensitive individuals who derive greater benefit from aggressive lipid lowering. Nature medicine • 2025-02-27	90.0	9	9	9	9
15	CXCL12 drives natural variation in coronary artery anatomy across diverse populations. Cell • 2025-03-07	90.0	9	9	9	9
16	Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction. Nature cardiovascular research • 2025-02-07	90.0	9	9	9	9
17	Demographic-Based Personalized Left Ventricular Hypertrophy Thresholds for Hypertrophic Cardiomyopathy Diagnosis. Journal of the American College of Cardiology • 2025-01-08	90.0	9	9	9	9
18	Small-molecule-induced ERBB4 activation to treat heart failure. Nature communications • 2025-01-11	89.0	10	9	8	9
19	Osimertinib induces reversible cardiac dysfunction through the GATA4-MYLK3-MYL2 axis. European heart journal • 2025-12-03	88.5	9	8	9	9
20	Piezo2 expressed in ganglionated plexi: Potential therapeutic target of atrial fibrillation. Heart rhythm • 2025-03-23	88.5	9	8	9	9
21	Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction. Circulation • 2025-03-12	88.5	9	8	9	9
22	An FDA-approved drug structurally and phenotypically corrects the K210del mutation in genetic cardiomyopathy models. The Journal of clinical investigation • 2025-02-17	88.5	9	8	9	9
23	Logic-based machine learning predicts how escitalopram attenuates cardiomyocyte hypertrophy. Proceedings of the National Academy of Sciences of the United States of America • 2025-03-04	88.5	9	8	9	9
24	Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy. Nature communications • 2025-04-16	88.5	9	8	9	9
25	Erythrocyte-derived extracellular vesicles induce endothelial dysfunction through arginase-1 and oxidative stress in type 2 diabetes. The Journal of clinical investigation • 2025-03-20	88.5	9	8	9	9
26	The Heart Has Intrinsic Ketogenic Capacity that Mediates NAD Circulation research • 2025-04-11	88.5	9	8	9	9
27	New Threshold for Defining Mild Aortic Stenosis Derived From Velocity-Encoded MRI in 60,000 Individuals. Journal of the American College of Cardiology • 2025-04-03	87.5	9	9	8	10
28	Artificial intelligence for individualized treatment of persistent atrial fibrillation: a randomized controlled trial. Nature medicine • 2025-02-15	87.0	8	9	9	9
29	The TRPM7 chanzyme in smooth muscle cells drives abdominal aortic aneurysm in mice. Nature cardiovascular research • 2025-02-15	87.0	9	8	9	8
30	Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis. Advanced science (Weinheim, Baden-Wurttemberg, Germany) • 2025-03-20	87.0	9	8	9	8
31	Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization. Advanced science (Weinheim, Baden-Wurttemberg, Germany) • 2025-03-24	87.0	9	8	9	8
32	Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes. The New England journal of medicine • 2025-03-31	87.0	8	9	9	9
33	Epigenetic alteration of smooth muscle cells regulates endothelin-dependent blood pressure and hypertensive arterial remodeling. The Journal of clinical investigation • 2025-03-27	87.0	9	8	9	8
34	Monocytes and interstitial macrophages contribute to hypoxic pulmonary hypertension. The Journal of clinical investigation • 2025-01-30	87.0	9	8	9	8
35	Transcatheter vs. surgical aortic valve replacement in women: the RHEIA trial. European heart journal • 2025-04-02	87.0	8	9	9	9
36	Macrophage WEE1 Directly Binds to and Phosphorylates NF-κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis. Advanced science (Weinheim, Baden-Wurttemberg, Germany) • 2025-04-09	87.0	9	8	9	8
37	Aficamten in Obstructive Hypertrophic Cardiomyopathy: A Multidomain, Patient-Level Analysis of the MAPLE-HCM Trial. Journal of the American College of Cardiology • 2025-12-05	87.0	8	9	9	9
38	Telemedicine-based integrated management of atrial fibrillation in village clinics: a cluster randomized trial. Nature medicine • 2025-02-22	87.0	8	9	9	9
39	Gain-of-function enhancer variant near KCNB1 causes familial ST-depression syndrome. European heart journal • 2025-04-10	87.0	9	8	9	8
40	Macrophage-mediated IL-6 signaling drives ryanodine receptor-2 calcium leak in postoperative atrial fibrillation. The Journal of clinical investigation • 2025-03-06	87.0	9	8	9	8
41	Impact of Heart Failure Severity on Vutrisiran Efficacy in Transthyretin Amyloidosis With Cardiomyopathy. Journal of the American College of Cardiology • 2025-03-18	87.0	8	9	9	9
42	Artificial intelligence-guided detection of under-recognised cardiomyopathies on point-of-care cardiac ultrasonography: a multicentre study. The Lancet. Digital health • 2025-02-01	86.0	9	9	8	9
43	Identifying biomarker-driven subphenotypes of cardiogenic shock: analysis of prospective cohorts and randomized controlled trials. EClinicalMedicine • 2025-01-13	86.0	9	9	8	9
44	Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes. Nature genetics • 2025-03-05	86.0	9	9	8	9
45	Ensemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images: PRESENT SHD. Journal of the American College of Cardiology • 2025-03-27	86.0	9	9	8	9
46	Apixaban versus aspirin for stroke prevention in people with subclinical atrial fibrillation and a history of stroke or transient ischaemic attack: subgroup analysis of the ARTESiA randomised controlled trial. The Lancet. Neurology • 2025-01-26	85.5	8	8	9	9
47	Cardiomyocyte PRL2 Promotes Cardiac Hypertrophy via Directly Dephosphorylating AMPKα2. Circulation research • 2025-02-14	85.5	9	7	9	8
48	Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases. Nature genetics • 2025-03-07	85.5	8	8	9	9
49	Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial. The lancet. Diabetes & endocrinology • 2025-01-17	85.5	8	8	9	9
50	Direct oral anticoagulants versus no anticoagulation for the prevention of stroke in survivors of intracerebral haemorrhage with atrial fibrillation (PRESTIGE-AF): a multicentre, open-label, randomised, phase 3 trial. Lancet (London, England) • 2025-03-03	85.5	8	9	9	8

About Scores

Innovation (0-10)

Degree of novel approaches or discoveries

Impact (0-10)

Potential impact on clinical practice

Rigor (0-10)

Robustness of research methodology

Citation (0-10)

Likelihood of being cited in future research