Daily Cosmetic Research Analysis

Thin film deposition is essential in the cosmetic industry, where formulations such as foundations and concealers rely on uniform layer formation to conceal pores and texture irregularities for a natural and even appearance. However, variations in skin topography, influenced by factors such as aging, genetics, and environmental exposure, can significantly affect the behavior of these films. Aging, in particular, leads to increased skin roughness and wrinkles, creating challenges to achieve consistent cosmetic deposition in diverse age groups. This study investigates the impact of age-related topographical changes on cosmetic thin film deposition and introduces a model for standardized, age-specific evaluation of cosmetic performance. Using X-ray microtomography, we compare skin topography from a cohort of the Korean population segmented into young and aged groups. A PDMS-based model is then constructed using these skin topographies, and thin film deposition is assessed both on human-derived skin positives and on the assembled model. This approach demonstrates the potential of artificial skin models for the precise quantification and evaluation of film coverage. In addition, we propose an improved model that incorporates key factors such as skin porosity and sebum production to increase realism. By exploring the interactions between skin morphology and cosmetic behavior, this method offers valuable insights into optimizing formulations to meet the diverse needs of consumers.

A four-round modified Delphi consensus was held concerning the question, 'What are the prerequisites for using ultrasound imaging in cosmetic filler injections'? Fifteen international experts in the field from seven different relevant medical specialties and 11 countries were included. An extensive list of topics was discussed in rounds 1 and 2. Statements were drawn up for voting in rounds 3 and 4. Experts had a consensus (>70% agreement) on most of the statements. With regard to equipment, a minimum linear 15 MHz transducer (probe) is recommended for both learning and regular diagnostics. Hand-held devices can be used in both circumstances. B-mode, Color-Doppler, Spectral Doppler, and picture/video archiving are mandatory, Power-Doppler is recommended. Experts find ultrasound imaging prior to injection mandatory in certain areas with high risk for vascular adverse events, as well as for the management of complications. It is recommended to identify prior fillers before injecting. An ultrasound-guided injection is recommended in many parts of the face for fillers, toxin and injection lipolysis. A sterile probe cover and sterile gel are necessary in these cases. Ultrasound-guidance is necessary for precise intralesional injections, needed in filler complication treatment. An extensive list of training and practice topics is given that should be learned before one can start using ultrasound imaging in cosmetic filler injection practice. Ultrasound imaging for minimal invasive aesthetic procedures has met a significant surge in attention, both in publication numbers and in prominence at major conferences. For physicians and institutions exploring this field, many critical decisions must be made, particularly concerning the prerequisites for using ultrasound imaging in cosmetic filler injections. Guidelines from international experts addressing these topics would provide valuable insights and facilitate the adoption of ultrasound technology in this field.

INTRODUCTION: Basal cell carcinoma (BCC) is the most common type of skin cancer globally, with its prevalence increasing due to chronic ultraviolet (UV) radiation exposure. Although surgical excision remains the cornerstone of treatment, achieving optimal outcomes requires a careful balance between complete tumor removal and the preservation of cosmetic appearance. OBJECTIVE: This study aims to investigate the relationship between excision margins, reoperation rates, and BCC recurrence through a retrospective analysis of 3036 surgical excisions. METHODS: Conducted at the Department of Plastic Surgery in Trieste, Italy, this study includes data from 2037 patients treated between 2014 and 2018. Excision procedures adhered to standardized hospital protocols. Tumor characteristics, excision margins, and involved anatomical sites were analyzed. RESULTS: The study demonstrated an equal gender distribution (51.02% women), with the nodular subtype (45.85%) being the most common. The head was the most frequently affected site (54.74%). A complete excision rate of 93.3% was achieved, but incomplete excisions were more common in head and neck locations and certain histological subtypes. Surgical reinterventions were primarily performed for high-risk BCCs, significantly reducing recurrence rates (0.52%). CONCLUSION: Reoperation, especially for high-risk BCCs, should be prioritized over conservative management to minimize recurrence. Narrow excision margins were associated with higher recurrence rates, highlighting the importance of adequate margin clearance. This study enhances understanding of the complex interplay between excision techniques, reoperation, and long-term outcomes in BCC management.