Daily Cosmetic Research Analysis

BACKGROUND: As a key genus in Zingiberaceae, Curcuma is widely studied for its taxonomic diversity, the presence of bioactive curcuminoids and volatile oils, and its extensive applications in traditional medicine and economic products such as spices and cosmetics. Although chloroplast genomes have been assembled and published for over 20 Curcuma species, mitochondrial genomic data remain limited. RESULTS: We successfully sequenced, assembled, and annotated the mitogenome of Curcuma amarissima (C. amarissima) using both Illumina short reads and Nanopore long reads, achieving the first complete mitogenome characterization in the Zingiberaceae family. The C. amarissima mitogenome features a unique multi-branched structure, spanning 6,505,655 bp and consisting of 39 distinct segments. It contains a total of 43 protein-coding genes, 63 tRNA genes, and 4 rRNA genes, with a GC content of 44.04%. Codon usage analysis indicated a weak bias, with neutrality plot analysis suggesting natural selection as a key factor shaping mitochondrial codon usage in C. amarissima. The mitogenome provides valuable insights into genome size, coding genes, structural features, RNA editing, repetitive sequences, and sequence migration, enhancing our understanding of the evolution and molecular biology of multi-branched mitochondria in Zingiberaceae. The high frequency of repeat sequences may contribute to the structural stability of the mitochondria. Comparing chloroplast genome, phylogenetic analysis based on the mitochondrial genome establishes a foundation for further exploration of evolutionary relationships within Zingiberaceae. CONCLUSIONS: In short, the mitochondrial genome characterized here advances our understanding of multi-branched mitogenome organization in Zingiberaceae and offers useful genomic resources that may support future breeding, germplasm conservation, and phylogenetic studies, though further research is necessary.

Oil palm (Elaeis guineensis) is a vital tropical crop widely utilized in food, cosmetics, and pharmaceuticals, owing to its high oil yield and economic importance. Understanding the dynamic lipid composition changes and regulatory mechanisms driving lipid biosynthesis during fruit development is crucial for enhancing oil quality and productivity. This study employed a comprehensive metabolomic and transcriptomic analysis to identify key regulators of lipid biosynthesis in oil palm. Lipid profiling using LC-MS/MS was conducted on mesocarp tissues at three critical developmental stages-95 days (MS1 and MT1), 125 days (MS2 and MT2), and 185 days (MS3 and MT3) post-pollination-in both seedless (MS) and thin (MT) oil palm varieties. A metabolomics study identified 30 metabolites during the development of MS and MT. Our findings reveal a complex interplay between metabolites and gene expression, with 8208 differentially expressed genes identified between the MS and MT varieties. Key lipid species, including saturated and unsaturated fatty acids, were detected throughout fruit development, with significant changes in their composition observed across the three developmental stages. Notably, correlation analysis between metabolites and gene expression uncovered significant associations, pinpointing candidate genes likely regulating lipid biosynthesis. Specifically, our results highlight the involvement of genes involved in fatty acid synthesis, lipid modification, and lipid transport, providing new insights into the molecular mechanisms governing lipid metabolism in oil palm. This research provides novel insights into the complex regulatory networks governing lipid biosynthesis in oil palm, highlighting potential targets for genetic improvement to optimize oil yield and quality, ultimately benefiting the food industry.

BACKGROUND: diabetic Wound is one of the most common complications throughout the world. .This experiment was conducted in order to study the effects of vitamin k cream on repair of full thickness wound in diabetic rat. METHODS: 75 adult Male Wistar rats were randomly divided into five groups of equal numbers; each group consists of 15 animals. After diabetes induction, full thickness wound in the shape of 2.25 CM2 square was created on the back of the rats. Group one was not treated and served as control. The woud areas in the second, third and fourth groups were covered twice a day with phenytoin (PHT) cream,0.05 and 1 % vitamin k creams, respectively. Group five treated with eucerin(vichel group) The size of wound area were measured in the 1, 4, 7, 10, 14, 18 and 21 days after wound induction. and histopathological observation and tissue parameters (hydroxyprolin(HP), collagen, glutation(GSH), malondialdeid (MDA), superoxiddesmutase(SOD), glutation peroxidase(GPX), catalase(CAT),tumor necrosis factor alpha (TNF-α), interlukin 1 bata(IL-1β)) were analysed as onther indicators of wound healing on days of 7, 14 and 21. RESULTS: the findings indicated that PHT and 1 % vitamin k creams significantly elevated HP and collagen in contrast with control group. furthermore, in all time points, the average wound size in PHT and 1 % vitamin k groups was significantly greater than other groups (P < 0.05). Also, PHT and vitamin K 1 % creams improved oxidative and inflammatory stress parameters at all times courses. Theses findings were confirmed by histological examination. CONCLUSION: The findings showed that 1 % vitamin k creams have potential effects on wound healing. Vitamin K exerts this effect through its antioxidant and anti-inflammatory properties, as well as stimulating collagen synthesis.