Daily Cosmetic Research Analysis

BACKGROUND: Mastopexy, with or without implants, is a common cosmetic breast surgery. Despite various techniques, long-term issues like pseudoptosis and recurrent ptosis remain challenging, especially in patients with poor skin quality or significant weight loss. While autologous methods provide stability, they often fall short in complex cases. Therefore, non-autologous reinforcement, such as acellular dermal matrices (ADMs) and synthetic meshes, are increasingly used. This systematic review critically evaluates the efficacy, safety, and outcomes of P4HB mesh in aesthetic breast surgery, focusing on postoperative complications and patient satisfaction. METHODS: This study followed Cochrane Handbook principles and PRISMA guidelines, with the protocol registered on PROSPERO (ID: CRD42024506060). Analyzing 183 patients (366 breasts) across seven studies, high heterogeneity, the absence of a control group, and a significant risk of bias precluded the possibility of conducting a meta-analysis, resulting in a systematic review instead. RESULT: This review evaluated the use of P4HB scaffolds in various breast surgeries, including mastopexy, augmentation, and revision procedures. Findings demonstrated improvements in breast support and lower pole stability over time. Complications were minimal. However, the studies highlighted outcome variability and the need for standardized assessment tools to measure results. CONCLUSIONS: The P4HB mesh offers notable advantages, including high biocompatibility, long resorption time, and cost-effectiveness, making it a promising option for challenging cases in aesthetic breast surgery. It provides internal support for soft tissues and implants, especially where implant visibility is a concern. However, due to the variability in surgical procedures and the lack of robust evidence, solid conclusions about the optimal clinical use of P4HB meshes are still premature, necessitating further high-quality studies.

INTRODUCTION: Endoscopic strip craniectomy followed by molding helmet therapy for sagittal suture synostosis is thought to be most effective in infants 3-4 months of age. However, infants often present to a neurosurgeon beyond this time period. The aim of this study was to compare morphological outcomes in older infants (5-7 months of age) with younger infants, in a series of babies who were operated endoscopically for sagittal suture synostosis. METHODS: The prospectively maintained Pediatric Neurosurgery Clinical Database at BC Children's Hospital was interrogated and 81 pediatric patients who had undergone an endoscopic craniectomy between 2010 and 2021 for sagittal craniosynostosis and had follow-up of at least 1 year were identified. Eleven of these patients received surgical intervention when they were 5 months of age or older (median 5.4 months, range 5.0-6.4). Morphological indices, duration of helmet therapy, and reoperation rates were compared between the early and late intervention groups. RESULTS: Both the early intervention (surgery before 5 months of age, n = 70) and the late intervention (surgery at 5 months or later, n = 11) groups had comparable average preoperative cephalic index (CI) (early - 67.1 vs. late - 69.4), change in CI (early - 6.7 vs. late - 4.7), and 2-year follow-up CI (early - 73.8 vs. late - 74.1). Both groups had similar average helmeting duration (6.6 vs. 6.1 months). Of the 11 late intervention patients, none required reoperation but poor cosmetic outcome was noted in 1 patient. The early intervention group had 1 patient who required a secondary cranial vault reconstruction due to persistent scaphocephaly. CONCLUSION: Infants who received an endoscopic craniectomy for sagittal suture synostosis after 5 months of age showed no statistically significant difference in morphological outcomes compared to the early intervention group.

BACKGROUND: The cosmetic surgery market has rapidly expanded owing to technological advancements and changes in aesthetic values. Minimally invasive procedures have gained substantial popularity among patients, with double-eyelid embedding being among the most common in Japan. This study used double-eyelid embedding as a model case to analyze market trends and demographics while evaluating the coronavirus disease 2019 pandemic's secondary effects. We elucidated time-series trends and the demographic patterns of double-eyelid embedding procedures in Japan, providing insights into overall cosmetic surgery market trends. METHODS: A retrospective multicenter analysis was conducted using data from 195,893 procedures performed between October 2020 and December 2024. Patient age, sex, occupation, and procedure date data were analyzed using autoregressive integrated moving average models and interrupted time-series analysis, incorporating multivariate regression to evaluate demographic impacts. RESULTS: An analysis of 195,893 double-eyelid embedding cases revealed a peak in demand in March 2023 and marked seasonality. The primary patient demographic comprised women in their 20s, with high demand among students and young office workers. Following the coronavirus disease 2019 pandemic, demand surged temporarily, then gradually stabilized over time, showing a downward trend. Time-series and multivariate analyses identified age, sex, and occupation as significant determinants of demand. CONCLUSIONS: This study highlighted the importance of demographic and seasonal factors that influence Japan's cosmetic surgery market. These findings contribute to improved clinical operations and marketing strategies, serving as a foundation for future research.