Daily Cosmetic Research Analysis

BACKGROUND: Double eyelid surgery is a common cosmetic procedure that creates a crease in the upper eyelid. Due to insufficient understanding of the procedure, numerous consultations have emerged, placing a heavy burden on plastic surgeons. The rise of large language models (LLMs) offers a potential solution to this issue. METHODS: This study collected sixteen questions commonly of concern to individuals seeking the surgery via an online questionnaire and assessed the efficacy of fifteen popular LLMs in answering these questions with both English and Chinese inputs. All responses from the LLMs were scored multidimensionally by three expert eyelid plastic surgeons across dimensions including professionalism, patient friendliness, informativeness, practicality, and logical clarity. The scoring results were statistically analyzed using the Friedman test and Nemenyi post-hoc test. RESULTS: With English input, ERNIE-Bot, ChatGPT-4o, and Gemini-2.0-Flash consistently ranked among the top three across most evaluation dimensions. In contrast, Claude-3.7-Sonnet, HuatuoGPT, ZoeGPT, CompliantGPT, and BastionGPT ranked lower across all dimensions, with performance significantly lagging behind the top performers. For Chinese input, DeepSeek-R1 maintained a leading position across all dimensions, forming the first tier alongside DeepSeek-V3, Gemini-2.0-Flash, and ERNIE-Bot. Meanwhile, Claude-3.5-Haiku, ZoeGPT, Llama3.3-70B-Instruct, CompliantGPT, HuatuoGPT, and BastionGPT ranked lower in multiple dimensions, with a significant gap relative to first-tier models. CONCLUSION: This study demonstrated LLMs' potential as medical consultation tools for double eyelid surgery, providing useful guidance for both English and Chinese users. Future research should focus on fine-tuning LLMs with more specialized medical data and exploring workflows for surgeon-LLM collaboration to validate their clinical utility. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

This study investigates how socioeconomic status, insurance type, and geography shape access to inpatient synthetic facial implant surgery in the United States. Using HCUP-NIS data from 2016 to 2020 (n=68), the authors show that lower-income patients are more likely to be publicly insured, experience significantly longer hospital stays, and are underrepresented in cosmetic and gender dysphoria-related procedures, while higher-income, urban patients more often self-pay for elective implants clustered in large metropolitan and Pacific regions. Despite low overall complication rates, inpatient admissions are associated with high costs, and rural and low-income patients face pronounced barriers to care, particularly for facial feminization surgery. This work highlights the need for broader outpatient data capture, qualitative research among marginalized groups, and standardized insurance coverage policies to promote equitable, cost-effective access to functional and aesthetic facial implant procedures.

Peloid is a matured mud with healing and/or cosmetic properties, composed of a complex mixture of mineral or seawater with a clay-based material, that requires quality control prior to its application in therapeutic and dermocosmetic treatments. In this research, physico-chemical and biological analyses were performed to assess influence of the two mineralized waters on three residual smectitic soils. Seawater increased the electrical conductivity values of peloids (from 0.3 to 0.5 mS/cm to 68.0-73.8 mS/cm) and their organic matter content (from 2.6 to 4.7% to around 7%), whereas thermo-mineral water enhanced the cation exchange capacity (from 38.4 to 70.0 meq/100 g to 55.2-86.6 meq/100 g). The pH of peloids remained alkaline, and zeta potential values were stable throughout the maturation period. The concentrations of Pb, Co, Ni and V in samples exceed the acceptable limits established for cosmetic and pharmaceutical products, hence further dermal bioacessibility assessment are required to substantiate their clinical safety before therapeutic use. Moreover, fecal indicator bacteria were not detected in the peloids, however thermo-mineral water peloids showed fungal contents slightly above recommended microbiological limits. The physico-chemical and microbiological characterization suggests that these peloids have potential therapeutic values, although further thermal and rheological characterization are required to assess their suitability.