Sepsis Research Analysis
Q1 2026 sepsis research converged on biology-informed triage, rapid bedside subphenotyping, and host-directed therapeutics. Pragmatic clinical implementation advanced with procalcitonin-guided ED workflows reducing 28-day mortality and a 1-hour IL-6/sTNFR1+bicarbonate panel enabling ARDS subphenotype assignment for precision enrollment. Parsimonious biomarker frameworks (cDIP) operationalized immune dysregulation and identified steroid-responsive patients, while multi-omic risk enrichment (BEYON