Daily Cosmetic Research Analysis
Three studies shape cosmetic and reconstructive practice today: a large prospective study shows that automated, rule-based screening robustly identifies body dysmorphic disorder risk in aesthetic surgery candidates; a PRISMA-compliant systematic review of randomized trials supports adipose-derived therapies for improving wound healing, scars, and patient-reported outcomes; and a 60-case series demonstrates the safety, feasibility, and oncologic adequacy of a retroauricular robotic neck approach
Summary
Three studies shape cosmetic and reconstructive practice today: a large prospective study shows that automated, rule-based screening robustly identifies body dysmorphic disorder risk in aesthetic surgery candidates; a PRISMA-compliant systematic review of randomized trials supports adipose-derived therapies for improving wound healing, scars, and patient-reported outcomes; and a 60-case series demonstrates the safety, feasibility, and oncologic adequacy of a retroauricular robotic neck approach that preserves cosmesis.
Research Themes
- Automated psychological risk screening in aesthetic surgery
- Adipose-derived therapies for wound and scar management
- Cosmesis-preserving robotic approaches in head and neck surgery
Selected Articles
1. Prospective Evaluation of an Automated Rule-based Screening Tool for Body Dysmorphic Disorder in Aesthetic Surgery.
In a prospective cohort of 3722 elective cosmetic patients, an automated rule-based system integrating the BDDQ flagged 29.0% as at risk for body dysmorphic disorder. Only eight BDD-positive patients proceeded to surgery after psychological evaluation, and 75% reported high satisfaction at a mean 15.7-month follow-up. Inter-rater agreement for classification, exclusion, and satisfaction was strong (κ 0.79–0.86).
Impact: This study operationalizes scalable, structured psychological screening in aesthetic surgery with large-sample, prospective data and strong reliability metrics, directly addressing safety and satisfaction risks linked to undiagnosed BDD.
Clinical Implications: Standardizing preoperative BDD screening (e.g., BDDQ plus rule-based algorithms) with mental health referral pathways may reduce postoperative dissatisfaction and complications by identifying high-risk patients before surgery.
Key Findings
- 3722 cosmetic surgery candidates were screened; 29.02% tested positive for BDD risk.
- Only 8 BDD-positive patients underwent surgery after psychological evaluation; 75% reported high satisfaction at mean 15.7 months.
- Strong inter-rater reliability for BDD classification (κ=0.86), exclusion decisions (κ=0.81), and satisfaction ratings (κ=0.79).
Methodological Strengths
- Large prospective cohort with standardized online dynamic questionnaire incorporating BDDQ
- Robust inter-rater reliability metrics across key decision points
Limitations
- Single-center practice limits generalizability and may introduce selection bias
- Rule-based algorithm requires external validation and calibration across diverse settings
Future Directions: Conduct multicenter validation with diverse populations, evaluate impact on adverse events and medico-legal outcomes, and refine algorithm thresholds to balance sensitivity/specificity.
BACKGROUND: Body dysmorphic disorder (BDD) is underdiagnosed in aesthetic surgery and poses significant risks for postoperative dissatisfaction and complications. Structured screening tools are required to improve early detection and guide surgical decision-making. This study evaluated the effectiveness of an automated, rule-based screening system incorporating the Body Dysmorphic Disorder Questionnaire (BDDQ) in a large cohort of patients undergoing cosmetic surgery. METHODS: This prospective study enrolled 3722 adult patients who underwent elective cosmetic procedures between January 2021 and July 2024 in a solo plastic surgery practice. The patients completed an online dynamic questionnaire, including the BDDQ. A rule-based algorithm integrates BDDQ scores with clinical variables to flag BDD risk. Patients with positive screening results underwent psychological assessments before surgical eligibility was determined. Postoperative outcomes were assessed using a multidimensional satisfaction questionnaire that included a visual analog scale. Inter-rater reliability was calculated for the exclusion and satisfaction ratings. RESULTS: Among the 3722 patients, 1080 (29.02%) tested positive for BDD. Only 8 BDD-positive patients underwent surgery after psychological evaluation, of whom 75% reported high satisfaction at follow-up (mean: 15.7 mo). Cohen κ indicated strong inter-rater agreement for BDD classification (κ = 0.86), exclusion decisions (κ = 0.81), and satisfaction (κ = 0.79). The prevalence aligns with the upper estimates in aesthetic surgery populations and reflects enhanced detection via structured screening. CONCLUSIONS: Automated rule-based BDD screening improves psychological risk detection and planning in aesthetic surgery. This approach supports early referral and may enhance patient safety and satisfaction. Therefore, multicenter validation is recommended.
2. Adipose tissue and fat-derived products in wound, ulcer, and scar management: a systematic review.
Following PRISMA, this systematic review identified 16 randomized clinical trials showing that adipose-derived therapies improve wound healing, reduce pain, and enhance cosmetic appearance, satisfaction, and health-related quality of life versus conventional care. Efficacy was observed across various wound and scar types, with a favorable safety profile, though standardized protocols and larger RCTs are needed.
Impact: Aggregating randomized evidence, this review elevates adipose-derived therapies from promising innovations to interventions with comparative benefits on healing and patient-centered outcomes, guiding protocol development and trial design.
Clinical Implications: Clinicians may consider adipose-derived cell or tissue products as adjunctive options for complex wounds and scars within standardized protocols or clinical trials, counseling patients on potential benefits and current evidence limitations.
Key Findings
- Sixteen randomized clinical trials were included after screening 589 records.
- Adipose-derived therapies improved wound healing rates, reduced pain, and enhanced cosmetic appearance, patient satisfaction, and HRQoL versus conventional care.
- Favorable safety was observed across different wound and scar types.
Methodological Strengths
- PRISMA-compliant methodology with multi-database search and PROSPERO registration
- Focus on randomized clinical trials enhances internal validity
Limitations
- Heterogeneity of interventions, comparators, and outcome measures limits meta-analytic synthesis
- Long-term safety and durability data remain sparse
Future Directions: Develop standardized protocols, core outcome sets, and conduct adequately powered multicenter RCTs with long-term follow-up to confirm effectiveness and safety.
INTRODUCTION: Adipose-derived therapies hold promise in addressing the increasing prevalence of skin wounds, scars, and ulcers. This systematic review, conducted following the PRISMA guidelines, evaluates the therapeutic potential of adipose derived stem cells for improving wound healing, scar development and ulcer management. METHODS: An extensive search was conducted across PubMed, EMBASE, Scopus, Web of Science, Cochrane Central, and LILACS. The search strategy employed a combination of keywords and Medical Subject Headings (MeSH) terms related to "adipose tissue", "fat derivatives", "ulcers", "wound healing", and their synonyms, covering articles published from inception to October 2024. Our search yielded 589 records, with 16 randomized clinical trials and two ongoing studies meeting inclusion criteria after screening and full-text assessment. RESULTS: Findings indicate that adipose-derived therapies significantly enhance wound healing, reduce pain, and improve cosmetic appearance, patient satisfaction, and health-related quality of life compared to conventional treatments. DISCUSSION: These therapies demonstrate efficacy across various wound types and scars, with a favorable safety profile. However, further standardized protocols and large-scale randomized trials are essential to validate these outcomes and assess longterm safety. While adipose-derived therapies show promise in enhancing wound healing and managing scars, ongoing research is essential to facilitate their integration into routine clinical practice. SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024503209, PROSPERO CRD42024503209.
3. Robotic neck surgery using retroauricular approach - Experience of 60 procedures.
In a retrospective series of 60 retroauricular robotic neck procedures (32 patients), complication rates, hospital stay (median 2 days), lymph node yields, and 3-year regional control (94.7% in malignant cases) were comparable to conventional approaches. Conversion occurred in 6.7% of cases, and complications were mostly transient and conservatively managed, supporting safety and feasibility with improved scar concealment.
Impact: This experience report provides medium-term oncologic outcomes and operative metrics supporting a cosmesis-preserving retroauricular robotic route as a safe alternative comparable to conventional neck surgery.
Clinical Implications: For appropriately selected head and neck cases, a retroauricular robotic approach can achieve hidden scars without compromising oncologic adequacy or safety, warranting inclusion in surgical planning where expertise and resources exist.
Key Findings
- Sixty retroauricular robotic procedures were performed in 32 patients; 62.5% had malignant disease.
- Median hospital stay was 2 days; conversion to open approach occurred in 6.7% of cases.
- Three-year regional control in malignant cases was 94.7%, with acceptable complication profile and high lymph node yields.
Methodological Strengths
- Comprehensive operative and oncologic metrics including lymph node yields and multi-year follow-up
- Real-world series demonstrating feasibility across diverse neck procedures
Limitations
- Retrospective single-institution design with potential selection bias
- No direct comparator arm or patient-reported cosmetic outcome measures
Future Directions: Prospective comparative studies incorporating patient-reported aesthetic outcomes, cost-effectiveness analyses, and learning-curve assessments are needed.
Remote access approaches to the neck have gained attention due to cosmetic concerns with conventional cervical incisions. Their safety, reproducibility, and oncologic outcomes remain to be fully validated. We retrospectively analyzed our initial experience with retroauricular robotic neck surgery using the Da Vinci system. Thirty-two patients were included. Data collected comprised demographics, procedure type, surgical features, and oncological follow-up. Thirty-five surgeries were performed: 13 posterolateral neck dissections (levels II-V) with central (VI), 5 modified radical dissections (I-V), 5 posterolateral dissections (II-V), and 1 super-selective neck dissection (I). Twelve neck dissections were combined with thyroidectomy. Additional procedures included 4 partial thyroidectomies, 3 submandibular gland resections, 3 schwannoma resections, and 1 branchial cyst excision, totaling 60 procedures. Twenty patients had malignant disease (62.5%). Median hospital stay was 2 days (range 1 9), similar to conventional approaches. Complications included 5 temporary nerve palsies, 1 lymphatic fistula, 1 transient hypoparathyroidism, and 1 minor flap necrosis, all managed conservatively; 1 hematoma required reoperation. Conversion to a conventional approach occured in 4 cases (6.7%). No additional intraoperative or postoperative complications were observed. The mean lymph node yield was 54 in posterolateral/radical dissections and 13 in central dissections. Median follow-up of malignant cases was 41.3 months (range 18-56), with a 3-year regional control rate of 94.7%. Our experience with 60 retroauricular robotic procedures demonstrates this approach to be safe, feasible, and oncologically effective, with complication rates, hospital stay, and oncological outcomes comparable to conventional surgery.